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Concomitant use of CRIXIVAN with lovastatin or simvastatin is contraindicated due to an increased risk of myopathy including rhabdomyolysisCaution should be exercised if CRIXIVAN is used concurrently with atorvastatin or rosuvastatinTitrate the atorvastatin and rosuvastatin doses carefully and use the lowest necessary dose with CRIXIVANSee PRECAUTIONSDRUG INTERACTIONS

Pain in your side or lower backblood in your urinepale skineasy bruising or bleedingconfusion or weaknesssigns of a new infectionsuch as fever or chillscoughor flu symptomsrapid heart rateincreased sweatingtremors in your handsanxietyfeeling irritablesleep problems.

Do not let anyone else take your medicationAsk your pharmacist any questions you have about refilling your prescription.

To explain how indinavir workswe need to first tell you some information about HIVWhen HIV infects a cellit takes control of that cellHIV then forces the cell to make many more copies of the virusTo make these copiesthe cell uses proteins called enzymesWhen the activity of these enzymes is reduced the production of HIV slows.

If indinavir and didanosine are administered concomitantlythey should be administered at least one hour apart on an empty stomachconsult the manufacturer’s product circular for didanosine

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