Selegiline is used to help control the symptoms of parkinson s disease pd; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance in people who are taking levodopa and carbidopa combination sinemet .
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General supportive measures should be employedalong with immediate gastric lavageIntravenous fluids should be administered judiciously and an adequate airway maintainedElectrocardiographic monitoring should be instituted and the patient carefully observed for the development of arrhythmiasif requiredappropriate antiarrhythmic therapy should be givenThe possibility that the patient may have taken other drugs as well as SINEMET should be taken into considerationTo dateno experience has been reported with dialysishenceits value in overdosage is not known.
These are serious side effectsYou may need urgent medical attentionSerious side effects are generally How much does chloroquine cost rare.
Cases of falsely diagnosed pheochromocytoma in patients on carbidopa levodopa therapy have been reported very rarelyCaution should be exercised when interpreting the plasma and urine levels of catecholamines and their metabolites in patients on levodopa or carbidopa levodopa therapy.
When levodopa is administered orallyit is rapidly decarboxylated to dopamine in extracerebral tissues so that only a small portion of a given dose is transported unchanged to the central nervous systemFor this reasonlarge doses of levodopa are required for adequate therapeutic effectand these may often be accompanied by nausea and other adverse reactionssome of which are attributable to dopamine formed in extracerebral tissues.
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