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The most commonly observed adverse reactions in CYMBALTA-treated patientsas defined abovewere nauseafatigueconstipationdry mouthinsomniasomnolenceand dizziness.

Antidepressants increased the risk of suicidal thinking and behaviorsuicidalityin short-term studies in children and adolescents with depression and other psychiatric disordersAnyone considering the use of duloxetine or any other antidepressant in a child or adolescent must balance this risk with the clinical needPatients who are started on therapy should be closely observed for clinical worseningsuicidalityor unusual changes in behavior.

Take the missed dose as soon as you rememberSkip the missed dose if it is almost time for your next scheduled doseDo not take extra medicine to make up the missed dose.

Some patients taking Cymbalta have developed liver problemsIn rare casesthis has lead to liver failure and deathContact your health care provider immediately if you develop any of the following symptoms while taking Cymbalta:

Cymbaltaduloxetineis a selective serotonin and norepinephrine reuptake inhibitor antidepressantSSNRIDuloxetine affects chemicals in the brain that may be unbalanced in people with depression.

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although the manufacturer advises a gradual reduction of dosage when discontinuing cymbalta, patients have found this to be nearly impossible.

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