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There are no data available regarding the effect of EVISTA on invasive breast cancer incidence in women with inherited mutationsBRCA1BRCA2to be able to make specific recommendations on the effectiveness of EVISTAEVISTA is not indicated for the treatment of invasive breast cancer or reduction of the risk of recurrenceEVISTA is not indicated for the reduction in the risk of noninvasive breast cancer.

What to doRaloxifene should not be used to reduce a woman’s risk of cardiovascular diseaseWomen prescribed the drug should be warned about the potential risk of strokeStroke risk calculatorse.gFramingham calculatorsallow women at high risk of stroke to be identifiedIn such womenas well as those with characteristics that would have allowed them entry into the trialBox 1and those with a prior history of cerebrovascular eventsincluding transient ischemic attacksor atrial fibrillationthe choice of alternate therapies for osteoporosis seems wise.

If you take calcium supplementsdo not take more than your doctor has prescribedTaking more calcium than recommended will not provide extra protection for your bonesand may cause serious side effects including kidney stones.

EVISTA should be used with caution in patients with hepatic impairmentsee WARNINGS AND PRECAUTIONS and CLINICAL PHARMACOLOGY

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