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Although both cat mrna and enzyme activity were detectable in the initial cultures of transformed chlamydiae, the authors failed to obtain stable transformants after selection with chloramphenicol for 4 passages.

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Bone marrow hypoplasiaincluding aplastic anaemia and deathhas been reported following topical use of chloramphenicolWhilst the hazard is a rare oneit should be borne in mind when assessing the benefits expected from the use of the compound.

PRESCRIBED FORChloramphenicol treats various infections caused by susceptible strains of SyphiHinfluenzaeEcoliNeisseria speciesStaphylococcus and StreptococcusspeciesRickettsialymphogranuloma-psittacosis group of organismsand other bacteria that cause bacteremiabacteria in bloodand meningitis.

If you have an allergy to chloramphenicol or any other part of chloramphenicolIf you are allergic to any drugs like this oneany other drugsfoodsor other substancesTell your doctor about the allergy and what signs you hadlike rashhivesitchingshortness of breathwheezingcoughswelling of facelipstongueor throator any other signsIf you have any of these health problemsBone marrow disease or low blood cell countsIf you are taking any drugs that can raise the chance of blood problemsThere are many drugs that can do thisAsk your doctor or pharmacist if you are not sure.

Chloramphenicol injection may cause a condition called gray syndrome in premature and newborn infantsThere have also been reports of gray syndrome in children up to age 2 and in newborns whose mothers were treated with chloramphenicol injection during laborSymptomswhich usually occur after 3 to 4 days of treatmentmay includestomach bloatingvomitingblue lips and skin due to lack of oxygen in the bloodlow blood pressuredifficulty breathingand deathIf treatment is stopped at the first sign of any symptomsthe symptoms may go awayand the infant may recover completelyTalk to your doctor about the risks of using this medication during labor or to treat babies and young children.

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repeat cultures were sterile, and the patient s previous regimen of iv chloramphenicol, metronidazole, and oral divalproex was continued.

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