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Corticosteroids should be used with great care in patients with known or suspected Strongyloidesthreadworminfestationcorticosteroid-induced immunosuppression may lead to Strongyloides hyperinfection and dissemination with widespread larval migrationoften accompanied by severe enterocolitis and potentially fatal gram-negative septicemianot for use in cerebral malaria.
When corticosteroids are administered concomitantly with potassium-depleting agentse.gamphotericin Bdiureticspatients should be observed closely for development of hypokalemiaIn additionthere have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure.
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